Optimation of Red Ginger (Zingiberofficinale Roxb) Extract Lozenges with Various Concentrations of Binding and Disintegrant Materials
DOI:
https://doi.org/10.53017/ujhs.173Keywords:
Lozenges, Red Ginger, Binding, DisintegrantAbstract
The red ginger plant through several studies is known to have potential as a medicinal plant because it contains oleoresin and flavonoid that can relieve symptoms of coughs and are also effective in curing symptoms of sore throat, especially sore throat. The use of medicinal plants are active ingredients in herbal medicinal preparations has been widely used, especially in tablet preparations. In this study, tablets were formulated in 3 formulations with varying concentrations of binder and disintegrant. The method used in the wet granulation’s method because the selection of the method is adjusted to the nature of the extract and excipients to be used. Based on the tablet evaluation results, it was shown that the 3 formulas only met the requirements for the size uniformity test and the disintegration time test.
Downloads
References
C. Saparinto and D. S. Hesty, Jahe. Jakarta: Penebar Swadaya, 2013.
Hapsoh, H. Yaya, and J. Elisa, Budidaya dan Teknologi Pascapanen Jahe. Medan: USU Press, 2008.
F. B. Paimin, Budidaya Pengolahan Perdagangan Jahe. Jakarta: Penebar Swadaya, 1991.
M. Heinrich, B. Joanne, G. Simon, and M. Elizabeth, Farmakognosi dan Fitoterapi. Jakarta: Penerbit EGC.
R. Voigt, Buku Pelajaran Teknologi Farmasi Edisi V. Yogyakarta: UGM Press, 1994.
Depkes RI, Farmakope Indonesia, Edisi V. Departemen Kesehatan Republik Indonesia, 2014.
F. Sadik, Tablets in King, R.E (Ed), Dispensing. Easton: Mark Publishing Company, 1984.
R. Voigt, Buku Pelajaran Teknologi Farmasi Edisi V, Cetakan II. Yogyakarta: UGM Press, 1995.
L. Lachman, H. A. Lieberman, and J. L. Kanig, Teori dan Praktek Farmasi Industri II, Edisi Keti. Jakarta: UI-Press, 1994.
J. T. Carstensen, Pharmaceutics of Solid and Solid Dosage Forms. New York: Intercience Publication Jhon Wiley and Sons, 1997.
G. S. Banker and N. R. Anderson, Tablet in the Theory and Practice of industrial Pharmacy, Edisi III. Jakarta: UI Press, 1994.
L. Lachman, H. A. Lieberman, and J. L. Kanig, The Theory and Practice of Industrial Pharmacy, Edisi III. Philadelphia: Lea & Febinger, 1986.
Depkes RI, Farmakope Indonesia, Edisi III. Jakarta: Departemen Kesehatan Republik Indonesia, 1979.
E. L. Parrot, Pharmaceutical Technology Fundamental Pharmaceutics, 3th ed. Minneapolis: Burgess Peblishing Company, 1971.
T. N. S. Sulaiman, Teknologi dan Formulasi Sediaan Tablet. Yogyakarta: Laboratorium Teknologi Farmasi, UGM Press, 2007.
A. Fudholi, “Metodologi Formulasi dalam Kompresi Direct, Majalah Medika, No. 7, Tahun 9.” Grafiti Press, Jakarta, 1983.
H. C. Ansel, Pengantar Bentuk Sediaan Farmasi, Edisi Keem. Jakarta: UI Press, 2008.
Syukri, Biofarmasetika. Yogyakarta: UII Press, 2002.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Dwi Bagus Pambudi, St. Rahmatullah, Novel Umarella, Hilda Fitria Wulandari, Dewi Safitri
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
